Generic Neoral is used for preventing the rejection of organ transplants (kidney, liver, and heart). This medicine is also used to treat psoriasis and rheumatoid arthritis in certain patients.

Cyclosporine is an immunosuppressant. Cyclosporine ophthalmic (for use in the eye) can increase tear production that has been reduced by inflammation in the eye(s). Cyclosporine ophthalmic is used to treat chronic dry eye that may be caused by inflammation.

Restasis® - ophthalmic emulsion containing 0.05% of cyclosporine, made by Allergan, which is indicated to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. Increased tear production was not seen in patients currently taking topical anti-inflammatory drugs or using punctal plugs.